If Uruguayan defenders manage to get the best of Cristiano Ronaldo and get him sent off early in the game, it might be effectively game over for Portugal in Russian Federation. Furthermore, both players leave Russian Federation still in search of their first goals in the tournament's knockout stages.
This is a side with excellent, Italian-based midfielders in Rodrigo Bentancur, Lucas Torreira and Matias Vecino.
Moreover, he can compete against them, as with four goals he surpasses Suarez (two) and Cavani (one), and of his 15 shots, seven have been on target, compared to the eight from the Uruguayans.
"I believe Cristiano Ronaldo is one of the best strikers in the world", Tabarez said.
Portugal's shrewd tactician Fernando Santos would not be too concerned about their draws against Spain and Iran en route to the Round of 16 as he is known to be happy with the tag of ugly ducklings.
There are many possible factors for Europe's grip on the World Cup, but South America's contribution to the world game is at least on a par with Europe, with so many of its players starring for European clubs.
"Oscar Tabarez is the longest-serving worldwide manager".
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WORLD CUP FACT: In the last four FIFA World Cups, the teams that reached the semi-final stage all won their final group match.
"We will take him seriously, but we will not be obsessed by it".
Free-kick to Uruguay as Nahitan Nandez goes down after a challenge.
The Barcelona striker burst down the flank and cut around his marker to find space at the edge of the box before crossing the ball back across goal for Cavani to head in at the far post.
Uruguay form: Uruguay qualified from the group phase with an unblemished record and are hoping to carry that momentum into the latter stages. The team are gelling superbly and Tabarez's only dilemma concerns the defence, where he may make a change.
Portugal: Portugal are well prepared and hopeful of delivering a big performance against Uruguay.
The South Americans, who won all three of their first round games to top their group, have so far been the impressive of the two and are the only team yet to concede goal at the tournament in Russian Federation.
After huffing and puffing his way through the opening two group matches, Uruguay's talisman Edinson Cavani has finally arrived at the party, and in some style.